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Dundee robotics platform hunts male contraceptive

Researchers at the University of Dundee have developed a bespoke robotics system to automate testing on potential male contraceptive drugs.

Described in eLife, the robotic screening platform uses a fast microscope and image-processing tools that precisely track the very fast movement of human sperm, allowing the effects of drugs to be accurately measured. The system was used to rapidly test the efficacy of the ReFRAME collection, one of the world’s largest collections of previously approved and clinically tested drugs. Around 13,000 drugs were tested to gauge their impact on both the motility (movement) and acrosome reaction (essential for fertilisation) of human sperm.

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